Nonampullary duodenal adenoma is relatively common in patients with familial adenomatous polyposis (FAP), but sporadic duodenal adenoma (SDA) is rare. Approximately 40% of duodenal adenomas are sporadic, and the remaining 60% present in patients with FAP.

Adenomas of the major duodenal papilla, also known as ampullary adenomas, can occur sporadically or in the context of genetic syndromes such as familial adenoma-tous polyposis (FAP).

2023年1月26日 · A duodenal adenoma is a non-cancerous type of polyp that starts in a part of the small intestine called the duodenum. It is considered a precancerous condition because it can turn into a type of cancer called adenocarcinoma over time.

Nonampullary duodenal polyps are found in up to 5% of all upper endoscopies; the vast majority are identified incidentally in asymptomatic patients. Although most are benign, adenomas are estimated to account for 10%–20% of these lesions.

Duodenal cancer is cancer that occurs in the first part of your small intestine (duodenum). In its early stages, duodenal cancer often causes no symptoms. As the tumor grows, it may block proper digestion.

In the duodenum, the most common benign lesion is adenoma including Brunner’s gland adenomas, followed by leiomyomas and lipomas. According to results published by Orlowska in 1995, the potential of these lesions becoming malignant poses a much more worrying problem than the clinical symptoms themselves.

2019年3月28日 · Duodenal adenomas (DAs) are the most frequently encountered polyps of the duodenum, at times associated with genetic syndromes and predominantly classified according to their location as non-ampullary or ampulllary.

Duodenal polyps are found in 0.1 % to 0.8 % of all upper endoscopies. Duodenal adenomas account for 10 % to 20 % of these lesions. They can be sporadic or occur in the setting of a hereditary predisposition syndrome, mainly familial adenomatous polyposis.

2024年11月15日 · Nonampullary duodenal adenomas associated with familial adenomatous polyposis should be considered for endoscopic resection based on size (≥1 cm), morphologic characteristics, advanced histology (ie, high-grade dysplasia), …

This review will discuss the epidemiology of duodenal adenomas, their endoscopic detection and diagnosis, and techniques for safe and effective endoscopic resection of ampullary and non-ampullary lesions.