The intestinal epithelium is the single cell layer that forms the luminal surface (lining) of both the small and large intestine (colon) of the gastrointestinal tract. Composed of simple columnar epithelium its main functions are absorption, and secretion.

The mucus layer and the intestinal epithelial cells represent the main determinants of the physical intestinal barrier and have a fundamental role in health. Various methods are available to evaluate the function of the intestinal barrier, but correlation of results across studies and methodologies remains difficult.

2014年2月25日 · Intestinal epithelial cells (IECs) provide a physical and biochemical barrier that segregates host tissue and commensal bacteria to maintain intestinal homeostasis. Secretory IECs support...

Intestinal epithelial cells (IECs) line the surface of intestinal epithelium, where they play important roles in the digestion of food, absorption of nutrients, and protection of the human body from microbial infections, and others. Dysfunction of IECs can cause diseases.

The intestinal epithelium is comprised of a single layer of columnar epithelial cells structurally organized in a manner that optimizes the efficient transfer of vital particles such as nutrients, water and ions between the lumen and the body.

2017年7月14日 · The intestine is the most highly regenerative organ in the human body, regenerating its lining, called the epithelium, every five to seven days. Continual cell renewal allows the epithelium to withstand the constant wear and tear it suffers while breaking down food, absorbing nutrients, and eliminating waste.

2017年5月26日 · Intestinal epithelial cells greatly contribute to the maintenance of the symbiotic relationship between gut microbiota and the host by constructing mucosal barriers, secreting various...

The intestinal epithelium is a highly dynamic tissue that provides both physical and chemical barriers to protect the intestinal mucosa and peripheral organs from commensal microbes or invading pathogenic microorganisms.

2023年5月5日 · The intestinal epithelium is a selective and efficient barrier between the luminal fluid, which contains bacteria and complex mixture of compounds of dietary and endogenous origin, and the bloodstream.

2025年1月1日 · Differentiated intestinal epithelial cells exhibit a diverse array of mechanisms that enable communication with surrounding cells, fortification against microorganisms, and orchestration of nutrient absorption and hormonal balance.