Mesenchymal stem cells (MSCs), also known as mesenchymal stromal cells or medicinal signaling cells, are multipotent stromal cells that can differentiate into a variety of cell types, including osteoblasts (bone cells), chondrocytes (cartilage cells), myocytes (muscle cells) and adipocytes (fat cells which give rise to marrow adipose tissue).

2023年5月24日 · Mesenchymal stem/stromal cells (MSCs) are of the most responsive cell populations to inflammation in tissues. MSCs are a kind of tissue stem cells that were initially identified in the...

Mesenchymal stromal cells (MSCs) are the spindle shaped plastic-adherent cells isolated from bone marrow, adipose, and other tissue sources, with multipotent differentiation capacity in vitro. However, whether MSCs truly qualify as stem cells is an area of some debate [1].

2019年12月2日 · Covas, D. T. et al. Multipotent mesenchymal stromal cells obtained from diverse human tissues share functional properties and gene-expression profile with CD146+ perivascular cells and...

2023年6月6日 · Stromal cells – also known as mesenchymal stem cells (MSCs) – are non-hematopoietic, multipotent, self-renewable cells that are capable of trilineage differentiation (mesoderm, ectoderm,...

5 天之前 · A multipotent and self-renewing population of spindle-shaped progenitor cells that can be isolated from various tissues and are capable of giving rise to multiple cell lineages under the appropriate differentiation media are known as marrow stromal cells or mesenchymal stromal cells (MSCs) [1, 2].Their unique properties, including regenerative capacity, immunomodulatory activity and relatively ...

One group of adult stem cells, mesenchymal stem or stromal cells (MSCs), has generated great interest in the fields of regenerative medicine and immunotherapy due to their unique biologic properties. MSCs were first discovered in 1968 by Friedenstein and colleagues 1 as adherent fibroblast-like cells in the bone marrow (BM) capable of ...

As a result of over five decades of investigation, mesenchymal stromal/stem cells (MSCs) have emerged as a versatile and frequently utilized cell source in the fields of regenerative medicine and tissue engineering. In this review, we summarize the ...

3 天之前 · Mesenchymal stromal/stem cells (MSC) have consistently demonstrated safety in clinical trials. However, demonstration of efficacy has been less consistent. Lu and Allickson summarize what has been learned about MSC biology as it applies to human therapy and provide insight into MSC therapies have been approved, to date, by regulatory agencies around the world.

2024年6月1日 · Mesenchymal stromal cells (MSCs) have become one of the most investigated and applied cells for cellular therapy and regenerative medicine.