Choline fenofibrate is a newly developed choline salt of fenofibric acid, which is more hydrophilic than fenofibrate. This study was initiated to evaluate the safety and efficacy of choline fenofibrate in comparison to micronized fenofibrate among Indian patients of mixed dyslipidemia.

Choline Fenofibrate is a choline formulation of fenofibrate, a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic activity.

2023年11月13日 · Fenofibrate is a medicine used with a cholesterol-reducing diet to lower high cholesterol and high triglyceride (fatty acid) levels in the blood. It works by increasing the breaking down and removal of triglycerides from the blood.

2024年11月20日 · Choline fenofibrate is a newly developed choline salt of fenofibric acid and is more hydrophilic than fenofibrate. It does not require first-pass hepatic metabolism to become active, as it dissociates to free fenofibric acid within the gastrointestinal tract and is rapidly absorbed throughout the gastrointestinal tract.

Fenofibric acid is a lipid-lowering agent that is used in severe hypertriglyceridemia, primary hyperlipidemia, and mixed dyslipidemia.

2024年11月8日 · Choline fenofibrate is the medication of choice for lowering triglyceride levels in the blood. It can reduce triglycerides by up to 50%. It decreases the risk of heart disease and helps prevent stroke and heart attack.

Fenofibrate is a third-generation fibric acid derivative indicated as a monotherapy to reduce elevated low-density lipoprotein cholesterol, total cholesterol, triglycerides, and apolipoprotein B; to increase high-density lipoprotein cholesterol in patients with primary hyperlipidemia or mixed dyslipidemia; and to reduce triglycerides in patients...

Choline fenofibrate is an antihyperlipedemic that is FDA approved for the treatment of primary hypercholesterolemia or mixed dyslipidemia and hypertriglyceridemia. Common adverse reactions include headache, back pain, nasopharyngitis, nausea, …

2024年12月10日 · Cholelithiasis: Fenofibric acid increases cholesterol excretion into the bile, leading to risk of cholelithiasis. If suspected, gallbladder studies are indicated (5.5). Coumarin anticoagulants: Use caution in concomitant treatment with oral coumarin anticoagulants.

Trilipix is indicated as adjunctive therapy to diet to reduce TG in patients with severe hypertriglyceridemia.