Chymotrypsinogen is an inactive precursor (zymogen) of chymotrypsin, a digestive enzyme which breaks proteins down into smaller peptides. Chymotrypsinogen is a single polypeptide chain consisting of 245 amino acid residues. [1] .

Chymotrypsin is synthesized in the pancreas. Its precursor is chymotrypsinogen. Trypsin activates chymotrypsinogen by cleaving peptidic bonds in positions Arg15 – Ile16 and produces π-chymotrypsin.

糜蛋白酶原（英语：Chymotrypsinogen），也叫胰凝乳蛋白酶原，是糜蛋白酶的无活性前体（酶原），糜蛋白酶是一种消化酶，可将蛋白质分解成更小的肽。 糜蛋白酶原是由245个 氨基酸 残基组成的单一 多肽 链。

胰凝乳蛋白酶原 chymotrypsinogen 为胰凝乳蛋白酶的前体物质。 牛的胰凝乳蛋白酶原A 氨基酸残基 245个，分子量24500。 白色结晶或粉末。 不含盐，由牛胰中提取而得。 每mg约含7000单位。 可被 胰蛋白酶 激活，但不被胰凝乳蛋白酶激活。 ,生化研究。 抗溃疡药。 平均价格大约是每毫克1.5元左右！ 胰凝乳蛋白酶原 chymotrypsinogen 为胰凝乳蛋白酶的前体物质。 牛的胰凝乳蛋白酶原A氨基酸残基245个，分子量24500。

Chymotrypsinogen is an inactive precursor of the enzyme chymotrypsin, which is synthesized as a 245 amino acid protein. Activation of chymotrypsinogen involves proteolytic cleavage at two sites, resulting in the formation of three chains held together by disulfide bonds.

chymotrypsinogen A) is a “hydrolytic enzyme” member of the super-family of serine proteases, enzymes that hydrolytically cleave peptide bonds utilizing a serine hydroxyl group as a nucleophile at the active site.

2024年12月24日 · CTRB1 (Chymotrypsinogen B1) is a Protein Coding gene. Diseases associated with CTRB1 include Pancreatitis and Pancreatic Acinar Cell Adenocarcinoma. Among its related pathways are Metabolism of water-soluble vitamins and …

2018年10月5日 · Chymotrypsin (EC 3.4.21.1) is a digestive enzyme that promotes proteolysis, or the breakdown of proteins and polypeptides. It is a serine protease synthesized in the pancreas and is a vital component in the pancreatic juice.

It has long been known that trypsin, one of the best-characterized serine proteinases, is produced as a zymogen (trypsinogen) in the acinar cells of the pancreas. It is secreted into the duodenum, activated into the mature form of trypsin by enterokinase, and functions as an essential food-digestive enzyme.

2023年7月27日 · This web page examines some of the structural properties of chymotrypsin, and it's corresponding zymogen-precurso r, chymotrypsinogen. Chymotrypsin, a digestive enzyme becomes activated after the proteolysis of the peptide bond between Arg15 and Ile16 in chymotrypsinogen by trypsin.