A foreign body granuloma forms when the host immune system is unable to digest the foreign body, resulting in the accumulation of macrophages and histiocytes. As macrophages surround and isolate the foreign body, some of them will fuse to form multinucleated giant cells.

A granuloma is an area of tightly clustered immune cells, or inflammation, in your body. They form around an infection or foreign object in your body. They can form almost anywhere, but they’re most often found in your lungs. Granulomas can be a …

2023年7月27日 · Foreign body granulomas represent a tissue granulomatous reaction to retained foreign bodies. Foreign body granulomas typically present as a tender mass 1. Granulatmous reactions aim to either resorb organic (e.g. wood,) or …

2021年6月30日 · When something penetrates the skin, eye, or other parts of the body, it can lead to a foreign body granuloma. This looks like a little lump at the site of the damage.

2019年3月13日 · The development of foreign body granulomas is thought to be under the control of both the humoral and cell-mediated immune system pathways and most likely represents a type IV hypersensitivity reaction to a foreign antigen.

2021年11月10日 · Foreign body granuloma is a cutaneous inflammatory response to exogenous material in the dermis or subcutis that has a low potential for degradation by macrophages. The foreign material is nonliving, inorganic, or organic material that is …

A foreign body granuloma is a non-allergic chronic inflammatory reaction that is mainly composed of multinucleated giant cells. Foreign body granulomas may occur after the administration of any dermal filler.

Foreign body granuloma is a tissue reaction in response to foreign objects penetrating the soft tissue. The forefoot is commonly involved especially in the pediatric age and in labor workers [87]. Plain radiographs can show soft tissue fullness (Fig. 12 a). If the foreign body is radiopaque and sizable, it may be apparent.

The differential diagnosis for bony reaction to an unrecognised organic foreign body includes osteoid osteoma, chronic and acute osteomyelitis, tuberculosis granuloma, bone cyst, aneurysmal bone cyst, cortical fibrous defect, and neoplasm.

The purpose of this article is to update dermatologists, pathologists, and other physicians on the most recent etiopathogenesis, clinical presentations, systemic associations, evaluation, and evidence-based management concerning foreign body granulomatous reactions of skin.