Methionine sulfoximine (MSO, also known as MetSox [1]) is an irreversible glutamine synthetase inhibitor. It is the sulfoximine derivative of methionine with convulsant effects. [2] Methionine sulfoximine is composed of two different diastereomers, which are L-S-Methionine sulfoximine and L-R-Methionine sulfoximine.

L-methionine sulfoximine is a methionine sulfoximine in which the amino group has S-stereochemistry. It has a role as a geroprotector and an EC 6.3.1.2 ( glutamate -- ammonia ligase) inhibitor. It is a methionine sulfoximine, a L-methionine derivative and a non-proteinogenic L-alpha-amino acid.

L-Methionine sulfoximine (MSX) enhances NH 3 production in seedling leaves wheat, barley, corn and sorghum plants by inhibiting GS activity. MSX increases ornithine decarboxylase activity and decreases the survival rate in a model of transient cerebral ischemia.

Methionine sulfoximine (MSO), a well-characterized inhibitor of glutamine synthetase, displays significant therapeutic benefits in animal models for several human diseases. This amino acid might therefore be a viable candidate for drug development to treat diseases for which there are few effective …

The compound L-methionine sulfoximine (MSX) has neurotoxic action and was found in the extract obtained from Cnestis ferruginea leaves (Garon et al., 2007) and in different parts of Cnestis palala (Murakoshi et al., 1993).

Methionine Sulfoximine is a compound that was first identified and synthesized as a toxic factor in wheat. It belongs to the group of sulfoximines, which are analogs of sulfones with unique bioactivity and structural properties.

L-Methionine sulfoximine certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland; CAS Number: 15985-39-4; Synonyms: L-S-(3-Amino-3 …

Sigma-Aldrich. GSS-1015. GS System 100mM L-Methionine sulfoximine, working range 25µM to 1mM

One possible inhibitor that might be used in humans to regulate either the endogenous or prokaryote forms of this enzyme is L-methionine-S,R-sulfoximine (MSO). A number of studies indicate that MSO is therapeutic in the treatment of hyperammonemia and …

2025年1月27日 · L-METHIONINE SULFOXIMINE (CAS 15985-39-4) information, including chemical properties, structure, melting point, boiling point, density, formula, molecular weight, uses, prices, suppliers, SDS and more, available at Chemicalbook.