2023年7月10日 · Manganese toxicity is unique neurotoxicity that progresses from early psychiatric abnormalities to symptoms reminiscent of Parkinson disease, such as postural deficiencies, bradykinesia, shuffling gait, mask-like facies, micrographia, and speech difficulties.

Manganism or manganese poisoning is a toxic condition resulting from chronic exposure to manganese. [1] . It was first identified in 1837 by James Couper. [2] Chronic exposure to excessive manganese levels can lead to a variety of psychiatric and …

2022年12月15日 · Too much manganese triggers oxidative stress, inflammation, as well as cognitive and reproductive issues. It can make infections more dangerous and lead to a Parkinson’s-like condition called manganism. Read on to find out more about manganese toxicity and ways to combat it. What is Manganese?

Manganese toxicity occurs when there is an excessive amount of manganese in the body. This condition can result from various factors, including environmental exposure, occupational hazards, or certain medical conditions.

People who consume water containing high levels of manganese (in some cases as high as 28 mg/L) have also developed manganese toxicity [4,40]. Manganese toxicity mainly affects the central nervous system and can cause tremors, muscle spasms, tinnitus, hearing loss, and the feeling of being unsteady on one’s feet [ 1 , 2 ].

Manganese toxicity is more often a risk with people who mine and refine ore, but even low-level occupational exposure and contaminated foods (eg, infant formula) or water may be harmful

2023年9月5日 · Manganese toxicity can occur due to occupational or environmental exposure to excessive levels of manganese. Understanding the causes, symptoms, and management strategies for manganese toxicity is essential for prevention, …

Pure manganese is a silver-colored metal; however, it does not occur in the environment as a pure metal. Rather, it occurs combined with other substances such as oxygen, sulfur, and chlorine. Manganese is a trace element and is necessary for good health.

Emerging data suggest that beyond traditionally recognized occupational manganism, Mn exposures and the ensuing toxicities occur in a variety of environmental settings, nutritional sources, contaminated foods, infant formulas, and water, …

Although many of the symptoms reported were characteristic of manganese toxicity, several aspects of this outbreak suggest that factors in addition to manganese may have contributed to the course of the disease. First, symptoms appeared to have developed very quickly.