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Novichok - Wikipedia
As nerve agents, the Novichok agents belong to the class of organophosphate acetylcholinesterase inhibitors. These chemical compounds inhibit the enzyme acetylcholinesterase, preventing the normal breakdown of the neurotransmitter acetylcholine.
Novichok | Description, History, Mechanism of Action, Toxicity,
2025年2月3日 · Novichok agents are anticholinesterases (also known as acetylcholinesterase inhibitors). They bind to the enzyme acetylcholinesterase and thereby prevent the destruction of the neurotransmitter acetylcholine within the nervous system.
What do we currently know about Novichoks? The state of the art
Novichok is the name given to the group of nerve agents created stealthily in the later phases of the Cold War by the Soviet Union. Constitute the fourth generation of chemical warfare agents; like other nerve agents, they are organophosphorus compounds designed to …
Novichok agents: a historical, current, and toxicological perspective
The Novichok, or “newcomer” class of nerve agents are lesser characterized, weaponized organophosphate agents. The use of known Novichok agents in warfare is banned under the Chemical Weapons Convention of 1997.
A-agents, misleadingly known as “Novichoks”: a narrative review
“Novichok” refers to a new group of nerve agents called the A-series agents. Their existence came to light in 2018 after incidents in the UK and again in 2020 in Russia. They are unique organophosphorus-based compounds developed during the …
Navalny 'poisoned': What are Novichok agents and what do they do? - BBC
2020年9月2日 · Some variants of Novichok are thought to be five to eight times more toxic than the VX nerve agent. "This is a more dangerous and sophisticated agent than sarin or VX and is harder to...
A-234 (nerve agent) - Wikipedia
A-234 is an organophosphate nerve agent. It was developed in the Soviet Union under the FOLIANT program and is one of the group of compounds referred to as Novichok agents that were revealed by Vil Mirzayanov.
What is Novichok, the rare nerve agent used in Russian spy attack - CNN
2018年3月13日 · According to Professor Gary Stephens, pharmacology expert at the University of Reading, Novichok is a more “dangerous and sophisticated” nerve agent than sarin which has been used in chemical...
Everything You Need To Know About Novichok - Radio Free …
2020年11月23日 · Novichok is a nerve agent developed at the GosNIIOKHT state chemical-research institute in Russia. It belongs to a broad class of compounds called cholinesterase inhibitors, which are...
What is Novichok? A neurotoxicologist explains - The Conversation
2018年7月13日 · The German government has announced that toxicology tests proved that the Russian opposition leader Aleksei Navalny was poisoned with Novichok, the same nerve agent used to poison former...