The palpebral fissure is the elliptic space between the medial and lateral canthi of the two open eyelids. In simple terms, it is the opening between the eyelids. In adult humans, this measures about 10 mm vertically and 30 mm horizontally.

2005年7月15日 · Clinical findings in a newborn with FAS include a characteristic pattern of facial anomalies, 6, 7 with short palpebral fissures, a thin upper lip, and a long, smooth philtrum (Figures 1, 2a...

If 2 of the 3 cardinal facial characteristics are present (short palpebral fissures, smooth philtrum, and/or thin vermilion border of the upper lip) the child is classified as having a positive dysmorphology facial evaluation for FASD.

2017年10月15日 · Characteristic facial dysmorphology associated with FASD includes short palpebral fissures (10th percentile or less for age and racial norms), a thin vermilion border of the upper lip, and a...

Short palpebral fissures. A shortened distance between the inner and outer corners of each eye, defined as a length two or more standard deviations below the mean. Normal measurements for palpebral fissure length are provided by the Hall Caucasian Charts 3. Measurement can be easily performed with a small ruler, although the examiner must ...

Short palpebral fissures may well reflect a defect in forebrain development rather than being proportionally reduced in size as a reflection of microcephaly. Keywords: palpebral fissure length, fetal alcohol syndrome (FAS), occipitofrontal circumference, forebrain development, microcephaly

Short palpebral fissures. Palpebral fissures are short when the distance between the medial and lateral canthi is more than 2 SD below the mean for age. A moderate reduction of the palpebral length may be the consequence of excessive curvature of the palpebral rim (“almond-shaped fissures”) and can be found in trisomy 21.

A form of congenital disorders of N-linked glycosylation characterized by generalized hypotonia, craniofacial dysmorphism (prominent occiput, short palpebral fissures, long eyelashes, broad nose, high arched palate, retrognathia), hypoplastic genitalia, seizures, feeding difficulties, hypoventilation, severe hypogammaglobulinemia with ...

Palpebral fissures are generally shortened and may slant up or down. Cataracts of unknown morphology have been reported and strabismus is common. The systemic phenotype is highly variable. Skull and facial anomalies are common with brachycephaly, bitemporal narrowing, and a broad low nasal bridge.

One of the most distinctive and consistent signs of FAS is found in the eyelids. Affected children often appear to have widely spaced eyes (figure 1), although measurements reveal that the eyes are normally situated. This discrepancy is caused by short palpebral fissures (eye openings).