The central dogma of molecular biology deals with the flow of genetic information within a biological system. It is often stated as "DNA makes RNA, and RNA makes protein", [1] although this is not its original meaning. It was first stated by Francis Crick in 1957, [2][3] then published in 1958: [4][5] The Central Dogma.

分子生物學 的中心法则 （英語： The central dogma of molecular biology，又譯 分子生物學的中心教条），首先由 佛朗西斯·克里克 於1958年 [1] 提出，並於1970年 [2] 在《自然》上的一篇文章中重申： The central dogma of molecular biology deals with the detailed residue-by-residue transfer of sequential information. It states that such information cannot be transferred from protein to either protein or nucleic acid.

In September 1957, Francis Crick gave a lecture in which he outlined key ideas about gene function, in particular what he called the central dogma. These ideas still frame how we understand life. This essay explores the concepts he developed in this influential lecture, including his prediction that we would study evolution by comparing sequences.

中心法则（英语：genetic central dogma），又译成分子生物学的中心教条（英语：The central dogma of molecular biology），首先由弗朗西斯·克里克于1958年提出，并于1970年在《自然》上的一篇文章中重申：“The central dogma of molecular biology …

2017年9月18日 · In September 1957, Francis Crick gave a lecture in which he outlined key ideas about gene function, in particular what he called the central dogma. These ideas still frame how we understand life. This essay explores the concepts he developed in this influential lecture, including his prediction that we would study evolution by comparing sequences.

2024年11月14日 · Francis Crick devised the “Central Dogma” in trying to understand a particular problem: protein synthesis, and specifically the flow of information in protein synthesis. 1 This great advance took place during the early days of the molecular biology revolution, when biologists were trying to understand the individual molecules of the cell ...

The central dogma of molecular biology deals with the detailed residue-by-residue transfer of sequential information. It states that such information cannot be transferred from protein to either...

3 天之前 · The fundamental theory of central dogma was developed by Francis Crick in 1958. His version was a bit more global and included the notion that information does not flow from proteins to nucleic acids. Scientists have since discovered several exceptions to the theory. On particularly notable example is that of prions.

Crick was an important theoretical molecular biologist and played a crucial role in research related to revealing the helical structure of DNA. He is widely known for the use of the term "central dogma" to summarise the idea that once information is transferred from nucleic acids (DNA or RNA) to proteins, it cannot flow back to nucleic acids ...

The central dogma of molecular biology deals with the detailed resid ue-by-residue t ransfer of sequential information. It states that such information cannot be transferred from protein to either protei n or nucleic acid. "The central dogma, enunciated by Crick in 1958 and the